Jordan Henderson and Raheem Sterling will miss England’s Nations League match against Iceland at Wembley on Wednesday because of injury.
Liverpool captain Henderson was replaced at half-time in England’s 2-0 defeat by Belgium on Sunday after feeling tightness in his leg.
Manchester City forward Sterling missed the match with a calf issue.
Both players will return to their clubs for further assessment before the Premier League resumes this weekend.
Manchester City are at Tottenham on Saturday (17:30 GMT) while Liverpool host Leicester on Sunday (19:15).
England manager Gareth Southgate will prepare for Wednesday’s match with a 22-man squad.
The Three Lions are unable to qualify for next October’s Nations League finals following their loss to Belgium in Leuven.