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Manchester United will face Betis, Sporting CP await Arsenal and six-time winners Sevilla meet unbeaten Fenerbahçe in the UEFA Europa League round of 16.
The draw was conducted on Friday at UEFA headquarters in Nyon, Switzerland.
Europa League last 16 draw:
Union Berlin vs Union Saint-Gilloise
Sevilla vs Fenerbahçe
Juventus vs Freiburg
Leverkusen vs Ferencváros
Sporting CP vs Arsenal
Man United vs Betis
Roma vs Real Sociedad
Shakhtar vs Feyenoord
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